Protein Purification
MilliporeSigma™ Calbiochem™ KB-R7943
A cell-permeable isothiourea derivative that inhibits the influx/reverse mode of Na+/Ca2+ exchangers (NCX; IC50
MilliporeSigma™ Calbiochem™ mTOR Activator, MHY1485
mTOR Activator, MHY1485, CAS Number: 326914-06-1, is a cell-permeable activator of mTOR that inhibits autophagy by suppressing the fusion between autophagosomes and lysosomes.
MilliporeSigma™ Calbiochem™ (±)-Ibuprofen
A nonsteroidal anti-inflammatory drug (NSAID) that acts as a reversible and competitive inhibitor of cyclooxygenase 1 (COX-1) (IC50 = 4.85 μM).
MilliporeSigma™ Calbiochem™ Apamin, Bee Venom
Polypeptide neurotoxin known to pass through the blood-brain barrier.
MilliporeSigma™ Calbiochem™ MMP-12 Inhibitor, MMP408
The MMP-12 Inhibitor, MMP408, also referenced under CAS 1258003-93-8, controls the biological activity of MMP-12. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Staurosporine, Streptomyces sp.
Staurosporine, CAS 62996-74-, is a cell-permeable, potent, reversible, ATP-competitive inhibitor of protein kinases (IC50 = 7, 20, 1.3, 0.7, & 8.5 nM for PKA, CAMK, MLCK, PKC, & PKG, respectively).
MilliporeSigma™ Calbiochem™ Caspase-1 Inhibitor IV
The Caspase-1 Inhibitor IV, also referenced under CAS 154674-81-4, controls the biological activity of Caspase-1. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ Latrunculin A, Latrunculia magnifica
Latrunculin A, CAS 76343-93-6, is a cell-permeable marine toxin that disrupts microfilament organization in cultured cells by the formation of a 1:1 complex with monomeric G-actin (KD = 200 nM).
MilliporeSigma™ Calbiochem™ Hydroxychloroquine Sulfate
A cell-permeable compound that increases intralysosomal pH and impairs autophagic degradation process. Suppresses proliferation of human dermal fibroblasts (IC50 = 30 μM).
MilliporeSigma™ Calbiochem™ Adenylyl Cyclase Type V Inhibitor, NKY80
The Adenylyl Cyclase Type V Inhibitor, NKY80, also referenced under CAS 299442-43-6, controls the biological activity of Adenylyl Cyclase Type V.
MilliporeSigma™ Calbiochem™ Autophagy Inhibitor IV, Cpd18
A cell-permeable 3-methyladenine (3-MA) derivative that acts as an autophagy inhibitor via the inhibition of class III PI3K, and without touching class I PI3K
MilliporeSigma™ Calbiochem™ MAP Kinase Inhibitor Set I
The MAP Kinase Inhibitor Set I controls the biological activity of MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Necrosis Inhibitor, IM-54
The Necrosis Inhibitor, IM-54, also referenced under CAS 861891-50-1, selectively blocks oxidative stress-induced necrotic cell death. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ MEK1/2 Inhibitor IV
The MEK1/2 Inhibitor IV, also referenced under CAS 212631-67-9, controls the biological activity of MEK1/2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ PARP Inhibitor VIII, PJ34
The PARP Inhibitor VIII, PJ34, also referenced under CAS 344458-15-7, controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications.